Lars O.G. Weidolf: search on Z-Library

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1

Pharmacokinetic Studies with Esomeprazole, the (S)-Isomer of Omeprazole

Dr Tommy Andersson, Mohammed Hassan-Alin, Göran Hasselgren, Kerstin Röhss, Lars Weidolf

Journal:

Clinical Pharmacokinetics

Year:

2001

Language:

english

File:

PDF, 241 KB

english, 2001

2

Use of Radiolabeled Compounds in Drug Metabolism and Pharmacokinetic Studies

Elmore, Charles S., Nilsson, Göran N., Isin, Emre M., Thompson, Richard A., Weidolf, Lars

Journal:

Chemical Research in Toxicology

Year:

2012

Language:

english

File:

PDF, 1.33 MB

english, 2012

3

Drug metabolism and pharmacokinetic strategies for oligonucleotide- and mRNA-based drug development

Andersson, Shalini, Antonsson, Madeleine, Elebring, Marie, Jansson-Löfmark, Rasmus, Weidolf, Lars

Journal:

Drug Discovery Today

Year:

2018

Language:

english

File:

PDF, 1.10 MB

english, 2018

4

Identification of felodipine metabolites in rat urine

Kurt-J. Hoffmann, Lars Weidolf

Journal:

Biological Mass Spectrometry = Journal of Mass Spectrometry (Wiley)

Year:

1985

Language:

english

File:

PDF, 843 KB

english, 1985

5

Determination of boldenone sulfoconjugate and related steroid sulfates in equine urine by high-performance liquid chromatography/tandem mass spectrometry

Lars O. G. Weidolf, Edgar D. Lee, Jack D. Henion

Journal:

Biological Mass Spectrometry = Journal of Mass Spectrometry (Wiley)

Year:

1988

Language:

english

File:

PDF, 607 KB

english, 1988

6

Screening, confirmation and quantification of boldenone sulfate in equine urine after administration of boldenone undecylenate (Equipoise™)

Lars O.G. Weidolf, Tina M.P. Chichila, Jack D. Henion

Journal:

Journal of Chromatography B: Biomedical Sciences and Applications

Year:

1988

Language:

english

File:

PDF, 871 KB

english, 1988

7

Bimodal column switching liquid chromatographic assay of six metabolites of [14C] felodipine in rat urine

Journal:

Journal of Chromatography B: Biomedical Sciences and Applications

Year:

1985

Language:

english

File:

PDF, 852 KB

english, 1985

8

Sensitive sulphur-specific detection of omeprazole metabolites in rat urine by high-performance liquid chromatography/inductively coupled plasma mass spectrometry

Berit Packert Jensen, Christopher Smith, Ian D. Wilson, Lars Weidolf

Journal:

Rapid Communications in Mass Spectrometry

Year:

2004

Language:

english

File:

PDF, 81 KB

english, 2004

9

Study of the electrospray ionization mass spectrometry of the proton pump inhibiting drug Omeprazole

Lars Weidolf, Neal Castagnoli Jr

Journal:

Rapid Communications in Mass Spectrometry

Year:

2001

Language:

english

File:

PDF, 270 KB

english, 2001

10

Mimicry of phase I drug metabolism – novel methods for metabolite characterization and synthesis

Tove Johansson, Lars Weidolf, Ulrik Jurva

Journal:

Rapid Communications in Mass Spectrometry

Year:

2007

Language:

english

File:

PDF, 225 KB

english, 2007

11

P450-catalyzed vs. electrochemical oxidation of haloperidol studied by ultra-performance liquid chromatography/electrospray ionization mass spectrometry

Tove Johansson Mali'n, Lars Weidolf, Neal Castagnoli Jr., Ulrik Jurva

Journal:

Rapid Communications in Mass Spectrometry

Year:

2010

Language:

english

File:

PDF, 169 KB

english, 2010

12

Comparison between electrochemistry/mass spectrometry and cytochrome P450 catalyzed oxidation reactions

Ulrik Jurva, Håkan V. Wikström, Lars Weidolf, Andries P. Bruins

Journal:

Rapid Communications in Mass Spectrometry

Year:

2003

Language:

english

File:

PDF, 167 KB

english, 2003

13

High-performance liquid chromatographic assay for human liver microsomal omeprazole metabolism

Tommy Andersson, Per-Olof Lagerstrøm, John O. Miners, Maurice E. Veronese, Lars Weidolf, Donald J. Birkett

Journal:

Journal of Chromatography B: Biomedical Sciences and Applications

Year:

1993

Language:

english

File:

PDF, 472 KB

english, 1993

14

In Vitro Approach to Assess the Potential for Risk of Idiosyncratic Adverse Reactions Caused by Candidate Drugs

Thompson, Richard A., Isin, Emre M., Li, Yan, Weidolf, Lars, Page, Ken, Wilson, Ian, Swallow, Steve, Middleton, Brian, Stahl, Simone, Foster, Alison J., Dolgos, Hugues, Weaver, Richard, Kenna, J. Gerr

Journal:

Chemical Research in Toxicology

Year:

2012

Language:

english

File:

PDF, 551 KB

english, 2012

15

Risk assessment and mitigation strategies for reactive metabolites in drug discovery and development

Richard A. Thompson, Emre M. Isin, Yan Li, Richard Weaver, Lars Weidolf, Ian Wilson, Alf Claesson, Ken Page, Hugues Dolgos, J. Gerry Kenna

Journal:

Chemico-Biological Interactions

Year:

2011

Language:

english

File:

PDF, 236 KB

english, 2011

16

Cytochrome P450-mediated activation of the fragrance compound geraniol forms potent contact allergens

Lina Hagvall, Jens Malte Baron, Anna Börje, Lars Weidolf, Hans Merk, Ann-Therese Karlberg

Journal:

Toxicology and Applied Pharmacology

Year:

2008

Language:

english

File:

PDF, 370 KB

english, 2008

17

Structural and mechanistic aspects of transcriptional induction of cytochrome P450 1A1 by benzimidazole derivatives in rat hepatoma H4IIE cells

Maria Backlund, Lars Weidolf, Magnus Ingelman-Sundberg

Journal:

Year:

1999

Language:

english

File:

PDF, 630 KB

english, 1999

18

Pharmacokinetics (PK) and effect on pentagastrin stimulated peak acid output (PAO) of omeprazole (O) and its 2 optical isomers, S-omeprazole/esomeprazole (E) and R-omeprazole (R-O)

Tommy Andersson, Eva Bredberg, Maria Sunzel, Madeleine Antonsson, Lars Weidolf

Journal:

Gastroenterology

Year:

2000

Language:

english

File:

PDF, 125 KB

english, 2000

19

Stereoselective Disposition of Proton Pump Inhibitors

Dr Tommy Andersson, Lars Weidolf

Journal:

Clinical Drug Investigation

Year:

2008

Language:

english

File:

PDF, 175 KB

english, 2008

20

State-of-the-art Tools for Computational Site of Metabolism Predictions: Comparative Analysis, Mechanistical Insights, and Future Applications

Afzelius, Lovisa, Hasselgren Arnby, Catrin, Broo, Anders, Carlsson, Lars, Isaksson, Christine, Jurva, Ulrik, Kjellander, Britta, Kolmodin, Karin, Nilsson, Kristina, Raubacher, Florian, Weidolf, Lars

Journal:

Drug Metabolism Reviews

Year:

2007

Language:

english

File:

PDF, 1.71 MB

english, 2007

21

Reactivity and risk assessment of CoA-conjugated carboxylic acid drugs

Darnell, Malin, Weidolf, Lars

Journal:

Toxicology Letters

Year:

2013

Language:

english

File:

PDF, 69 KB

english, 2013

22

Liquid-solid extraction conditions predicted by liquid chromatography for selective isolation of sulfoconjugated steroids from equine urine

Weidolf, Lars O. G., Henion, Jack D.

Journal:

Analytical Chemistry

Year:

1987

Language:

english

File:

PDF, 679 KB

english, 1987

23

Metabolism of Xenobiotic Carboxylic Acids: Focus on Coenzyme A Conjugation, Reactivity, and Interference with Lipid Metabolism

Darnell, Malin, Weidolf, Lars

Journal:

Chemical Research in Toxicology

Year:

2013

Language:

english

File:

PDF, 1.22 MB

english, 2013

24

Electrochemical Generation of Electrophilic Drug Metabolites: Characterization of Amodiaquine Quinoneimine and Cysteinyl Conjugates by MS, IR, and NMR

Jurva, Ulrik, Holmén, Anders, Grönberg, Gunnar, Masimirembwa, Collen, Weidolf, Lars

Journal:

Chemical Research in Toxicology

Year:

2008

Language:

english

File:

PDF, 448 KB

english, 2008

25

Determination of sulfonated azo dyes by liquid chromatography/atmospheric pressure ionization mass spectrometry

Bruins, Andries P., Weidolf, Lars O. G., Henion, Jack D., Budde, William L.

Journal:

Analytical Chemistry

Year:

1987

Language:

english

File:

PDF, 724 KB

english, 1987

26

Conference Report: High-resolution MS in drug discovery and development: current applications and future perspectives

Weston, Daniel J, Weidolf, Lars

Journal:

Year:

2012

Language:

english

File:

PDF, 297 KB

english, 2012

27

Electrochemical generation of drug metabolites with applications in drug discovery and development

Jurva, Ulrik, Weidolf, Lars

Journal:

TrAC Trends in Analytical Chemistry

Year:

2015

Language:

english

File:

PDF, 687 KB

english, 2015

28

Troglitazone metabolism and transporter effects in chimeric mice: a comparison between chimeric humanized and chimeric murinized FRG mice

Samuelsson, Kristin, Pickup, Kathryn, Sarda, Sunil, Foster, John R., Randall, Kevin, Abrahamsson, Anna, Jacobsen, Matt, Weidolf, Lars, Wilson, Ian

Journal:

Year:

2014

Language:

english

File:

PDF, 1.07 MB

english, 2014

29

Significantly Different Covalent Binding of Oxidative Metabolites, Acyl Glucuronides, and S-Acyl CoA Conjugates Formed from Xenobiotic Carboxylic Acids in Human Liver Microsomes

Darnell, Malin, Breitholtz, Katarina, Isin, Emre M., Jurva, Ulrik, Weidolf, Lars

Journal:

Chemical Research in Toxicology

Year:

2015

Language:

english

File:

PDF, 2.07 MB

english, 2015

30

Oxetane Substrates of Human Microsomal Epoxide Hydrolase

Toselli, Francesca, Fredenwall, Marlene, Svensson, Peder, Li, Xue-Qing, Johansson, Anders, Weidolf, Lars, Hayes, Martin A.

Journal:

Drug Metabolism and Disposition

Year:

2017

Language:

english

File:

PDF, 1.01 MB

english, 2017

31

The metabolic fate of fenclozic acid in chimeric mice with a humanized liver

Ekdahl, Anja, Weidolf, Lars, Baginski, Matthew, Morikawa, Yoshio, Thompson, Richard A., Wilson, Ian D.

Journal:

Archives of Toxicology

Year:

2018

Language:

english

File:

PDF, 805 KB

english, 2018

32

Corrigendum to ‘Drug metabolism and pharmacokinetic strategies for oligonucleotide- and mRNA-based drug development’ Drug Discovery Today 23 (2018) 1733–1745

Andersson, Shalini, Antonsson, Madeleine, Elebring, Marie, Jansson-Löfmark, Rasmus, Weidolf, Lars

Journal:

Drug Discovery Today

Year:

2018

Language:

english

File:

PDF, 298 KB

english, 2018

33

Hip to be square: oxetanes as design elements to alter metabolic pathways

Toselli, Francesca, Fredenwall, Marlene, Svensson, Peder, Li, Xue-Qing, Johansson, Anders, Weidolf, Lars, Hayes, Martin A

Journal:

Journal of Medicinal Chemistry

Year:

2019

Language:

english

File:

PDF, 989 KB

english, 2019

34

Metabolism of Strained Rings: Glutathione S -transferase–Catalyzed Formation of a Glutathione-Conjugated Spiro-azetidine without Prior Bioactivation

Li, Xue-Qing, Grönberg, Gunnar, Bangur, Eva-Henriette, Hayes, Martin A., Castagnoli, Neal, Weidolf, Lars

Journal:

Drug Metabolism and Disposition

Year:

2019

Language:

english

File:

PDF, 918 KB

english, 2019

35

Qualification of impurities based on metabolite data

Weidolf, Lars, Andersson, Thomas, Bercu, Joel P., Brink, Andreas, Glowienke, Susanne, Harvey, James, Hayes, Martin A., Jacques, Pascale, Lu, Chuang, Manevski, Nenad, Muster, Wolfgang, Nudelman, Raphae

Journal:

Regulatory Toxicology and Pharmacology

Year:

2019

Language:

english

File:

PDF, 1.30 MB

english, 2019

36

S11.4 - Management of mist in a case of multiple metabolic species differences

Journal:

Drug Metabolism and Pharmacokinetics

Year:

2020

File:

PDF, 30 KB

2020